Glutathione

Glutathione: Master Antioxidant and Cellular Protector

Molecular Overview

Glutathione (GSH) is a tripeptide composed of glutamine, cysteine, and glycine, synthesized endogenously in nearly every cell.

It functions as a primary intracellular antioxidant, maintaining redox homeostasis, neutralizing reactive oxygen species (ROS), and protecting cellular macromolecules from oxidative damage.

Glutathione also serves as a critical cofactor for detoxification enzymes such as glutathione peroxidase and glutathione-S-transferase, supporting the elimination of toxins, xenobiotics, and metabolic waste.

Age, oxidative stress, illness, and environmental toxins can deplete GSH levels, compromising cellular integrity, immune function, and metabolic balance.

Mechanism of Action

1. Antioxidant Defense

• Directly scavenges reactive oxygen and nitrogen species, preventing oxidative damage to lipids, proteins, and DNA.
• Maintains the reduced intracellular environment, critical for proper enzymatic and metabolic function.

2. Detoxification

• Conjugates with xenobiotics and endogenous toxins via glutathione-S-transferase, facilitating hepatic and cellular detoxification.
• Enhances elimination of heavy metals and oxidative byproducts.

3. Immune Support

• Modulates immune cell function, including lymphocyte proliferation and natural killer cell activity.
• Supports inflammatory balance, reducing chronic oxidative stress-mediated immune dysfunction.

4. Cellular Repair and Longevity

• Participates in DNA repair, protein synthesis, and mitochondrial maintenance, supporting cellular regeneration.
• Protects against age-related oxidative stress, contributing to healthy aging and tissue resilience.

Physiological and Clinical Benefits

• Antioxidant Protection: Shields cells from oxidative damage and free radical accumulation.
• Detoxification Support: Enhances liver function and waste elimination at the cellular level.
• Immune Optimization: Improves immune cell performance and inflammatory regulation.
• Cellular Repair and Longevity: Facilitates DNA repair, protein synthesis, and mitochondrial health.
• Skin and Metabolic Health: Supports clearer skin, reduced hyperpigmentation, and improved metabolic function.

Therapeutic and Research Applications

Glutathione supplementation or intravenous therapy is commonly applied for:

• Detoxification and liver support
• Anti-aging and oxidative stress mitigation
• Immune system enhancement
• Recovery from physical or metabolic stress
• Skin health and aesthetic improvement

Glutathione functions as a central regulator of redox balance, detoxification, and cellular resilience, integrating antioxidant protection, immune support, and regenerative mechanisms for overall systemic wellness.

Legal Policy: 

This product is strictly for research purposes only and is intended solely for in vitro testing and laboratory experimentation. The information provided on this website is for educational use and does not permit the introduction of this product into humans or animals. Handling of this product is restricted to licensed and qualified professionals. It is not classified as a drug, food, or cosmetic, and should not be misrepresented or used as such.

All products sold on this site are for research and development use only. They are not intended for human or animal use.

The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.

Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.

Molecular Formula

• Formula: C₁₀H₁₇N₃O₆S
• Molecular Weight: 307.33 g/mol
• Amino Acid Sequence: γ‑Glu‑Cys‑Gly (a tripeptide with a gamma peptide bond)

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1. What is Glutathione, and why does it matter?

Glutathione is a powerful antioxidant naturally produced in the body. It's essential for detoxification, immune support, and protecting your cells from oxidative stress and damage. As we age or face stress, illness, or environmental toxins, glutathione levels can drop, which may impact energy, skin health, and overall wellness.

2. What are the benefits of Glutathione?

Glutathione is often called the body’s “master antioxidant” because it plays such a vital role in health. Potential benefits include:

• Detoxification of the liver and cells

• Brightened, clearer skin and reduced hyperpigmentation

• Improved energy and reduced oxidative stress

• Stronger immune function

• Slower signs of aging and cellular damage

It’s especially popular for anti-aging, skincare, and recovery support.

3. What is Glutathione used for?

Glutathione is commonly used to:

• Support liver detox and immune health

• Improve skin tone, texture, and clarity

• Enhance recovery from stress, illness, or exercise

• Combat free radicals and promote anti-aging

• Support neurological and metabolic function

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